The minimally invasive, first-line treatment for vesicoureteral reflux (VUR), a malformation of the ureteral tunnel in the bladder affecting 1% of children worldwide. VUR can allow infected urine to upflow into the kidneys, which can lead to severe infections of the urinary tract and irreversible kidney damage. Deflux for VUR is available in the United States, Australia, Canada, Europe, Latin America, New Zealand and Japan.